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Home      Products     Agrochemicals       112636-83-6 Dicyclanil
  • 112636-83-6 Dicyclanil
  • 112636-83-6 Dicyclanil
  • 112636-83-6 Dicyclanil
  • 112636-83-6 Dicyclanil
112636-83-6 Dicyclanil112636-83-6 Dicyclanil112636-83-6 Dicyclanil112636-83-6 Dicyclanil

112636-83-6 Dicyclanil

Product Name: Dicyclanil
Synonyms: DICYCLANIL;4,6-Diamino-2-cyclopropylaminopyrimidine-5-carbonitrile;5-Pyrimidinecarbonitrile, 4,6-diamino-2-(cyclopropylamino)-;4,6-DIAMINO-2-(CYCLOPROPYLAMINO)-5-PYRIMIDINECARBONITRILE;Dicyclani;icyclanil;Dicyclanil 10 μg/mL in Acetonitrile;Dixinier
CAS: 112636-83-6
MF: C8H10N6
MW: 190.21
EINECS: 214-921-2
Product Categories: pyrimidine;Heterocycle-Pyrimidine series;API
Mol File: 112636-83-6.mol
Dicyclanil Structure
Dicyclanil Chemical Properties
Boiling point  543.6±60.0 °C(Predicted)
density  1.44±0.1 g/cm3(Predicted)
storage temp.  Keep in dark place,Inert atmosphere,2-8°C
solubility  DMSO: 38 mg/mL (199.78 mM);Ethanol: 2 mg/mL (10.51 mM)
form  neat
pka 4.09±0.50(Predicted)
Water Solubility  Water: Insoluble
BRN  9265760
CAS DataBase Reference 112636-83-6(CAS DataBase Reference)
Safety Information
Hazard Codes  Xn;N,N,Xn
Risk Statements  20/22-51/53
Safety Statements  36/37/39-61
RIDADR  UN 3077
WGK Germany  2
MSDS Information
Dicyclanil Usage And Synthesis
Description Dicyclanil is an insect growth regulator belonging to the group of pyrimidinamines.
Dicyclanil is a pyrimidin derivative. Dicyclanil is an insect development inhibitor very specific for the prevention of blowfly strike in sheep. It does not control any other external parasites of sheep. It is used mainly as a spray-on. It is not used in other livestock, horses or pets.
Uses Dicyclanil is a veterinary medication for the protection against early season myiasis.
Application Dicyclanil may be used as an analytical reference standard for the quantification of the analyte in biological samples, bovine, porcine and chicken muscle using various chromatography techniques.
Pharmacokinetics Dicyclanil has a long lasting action which interferes with moulting and pupation in dipteran species. However, the precise mode of action of this compound on ectoparasites is not known.
A variety of in vitro and in vivo pharmacodymanic tests were performed with dicyclanil in rats, mice and guinea pigs. In vitro, dicyclanil was devoid of significant effects on the neuromuscular junction at concentrations below 3 mM. Slight antagonistic effects on smooth muscle were reported at concentration levels above 0.1 mM. Dicyclanil caused a statistically significant increase in heart rate, tidal volume and minute volume at a dose level of 100 mg/kg bw in studies on the cardiovascular and respiratory systems in the rat. In various in vivo studies, dicyclanil was devoid of significant effects on behavior at a dose level of 1 mg/kg bw in mice.
Toxicity evaluation Dicyclanil was investigated in a series of acute toxicity studies. The acute LD50 by the oral route in the rat was 520 mg/kg bw. The acute LD50 by the dermal route was greater than 2000 mg/kg bw in the rat. An acute inhalation toxicity study also conducted in the rat showed the acute LC50 to be 3,184 mg/m3 of air. The toxic effects were dyspnoea and reduced locomotor activity.
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