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Home      Products     Agrochemicals       89-00-9 Quinolinic acid
  • 89-00-9 Quinolinic acid
  • 89-00-9 Quinolinic acid
  • 89-00-9 Quinolinic acid
  • 89-00-9 Quinolinic acid
89-00-9 Quinolinic acid89-00-9 Quinolinic acid89-00-9 Quinolinic acid89-00-9 Quinolinic acid

89-00-9 Quinolinic acid

  • Product Item : 89-00-9 Quinolinic acid
  • Category： Agrochemicals
  • Purity:99%
  • Package:100g ,1kg ,5kg, 25kg
  • Crystalline Powder White to light yellow-beige
  • INQUIRY   EMAIL
Product Name: Quinolinic acid
Synonyms: 2,3-PyridinedicarboxylicAcid99%;QuinolinicAcid>99%;Pyridin-2,3-dicarbonsaeure;2,3-Pyridinedicarboxylic;2,3-PYRIDINEDICARBOXYLIC ACID (QUINOLINIC ACID);2,3-pyridine dicarbo;2,3-PYRIDINEDICARBOXYLIC ACID;AKOS BBS-00003814
CAS: 89-00-9
MF: C7H5NO4
MW: 167.12
EINECS: 201-874-8
Product Categories: Pyridine series;Pyridine;pyridine derivative;Carboxylic Acids;Pyridines;Heterocyclic Compounds;Medical Intermediates;Heterocycles;Inhibitors;Carboxylic Acids;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Pesticides intermediate;Pyrimidines
Mol File: 89-00-9.mol
Quinolinic acid Structure
Quinolinic acid Chemical Properties
Melting point  188-190 °C (dec.) (lit.)
Boiling point  295.67°C (rough estimate)
density  1.5216 (rough estimate)
refractive index  1.6280 (estimate)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  10g/l
pka 2.43(at 25℃)
form  Crystalline Powder
color  White to light yellow-beige
Odor odorless
Water Solubility  0.55 g/100 mL
Merck  14,8073
BRN  137110
InChIKey GJAWHXHKYYXBSV-UHFFFAOYSA-N
CAS DataBase Reference 89-00-9(CAS DataBase Reference)
EPA Substance Registry System 2,3-Pyridinedicarboxylic acid (89-00-9)
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38-33
Safety Statements  26-36/37-24/25-37
WGK Germany  3
RTECS  US7967250
TSCA  T
HazardClass  IRRITANT
HS Code  29333999
Hazardous Substances Data 89-00-9(Hazardous Substances Data)
Toxicity Focal injection of quinolinic acid into specific areas of the brain produces neuronal damage although sparing axons of passage. Similarities between the biochemical and morphological profiles of these lesions and human neuropathy seen in neurodegenerative diseases have led to the proposal that endogenous excitotoxins may play a role in such neurodegenerative disease states. Quinolinic acid is an intermediate in the kynurenine pathway of tryptophan metabolism and has been detected in the brains of several mammals including man. The neuroexcitatory action is thought to be mediated via interaction with the N-methyl-D-aspartate (NMDA) receptor of the glutamate family. No mechanism for quinolinic acid removal, nor for synaptic inactivation, has been found, and consequently accumulation of concentrations capa_x0002_ble of inducing neuronal degeneration and death may occur.
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